hrp0082p2-d3-490 | Endocrine Oncology | ESPE2014

Genetic Susceptibility in Autoimmune Polyglandular Syndrome Type 3 Variant

Babiker Amir , Gadi Iman Al , Jurayyan Nasir Al , Mohamed Sarar , Al Otaibi Hessah , Hussain Khalid

Background: Autoimmune polyglandular syndrome type 3 (APS3) comprises a wide spectrum of autoimmune endocrine disorders other than adrenal insufficiency. It includes the association of autoimmune thyroid disease (ATD) with type 1 diabetes (T1D) which is known as APS3 variant (APSA3v). Genes linked to possible joint susceptibility for APS3v have been reported in few cases. We report a 10-year-old girl with GravesÂ’ disease (GD) who developed T1D after 6 years of the diagnos...